托彻普 - CAS:262352-17-0 - CAS号查询_生物试剂_化学试剂_分析试剂

中文名称:	托彻普
英文名称:	Torcetrapib
别名:	托彻普;(2R,4S)-4-[(3,5-双三氟甲基苄基)甲氧基甲酰氨基]-2-乙基-6-三氟甲基-3,4-二氢-2H-喹啉-1-羧酸乙酯 CP529414;ethyl (2R,4S)-4-[[3,5-bis(trifluoroethyl)phenyl]ethyl-ethoxycarbonylaino]-2-ethyl-6-(trifluoroethyl)-3,4-dihydro-2H-quinoline-1-carboxylate
CAS No:	262352-17-0	分子式:	C₂₆H₂₅F₉N₂O₄	分子量:	600.48
CAS No:	262352-17-0
分子式:	C₂₆H₂₅F₉N₂O₄
分子量:	600.48

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T10479 托彻普 ≥98% (psaitong)

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包装规格：

5mg 25mg 100mg in glass bottle

溶解性：

溶于DMSO(≥100mg/mL )

产品描述：

一种高效的CETP抑制剂，IC50:37n。
Torcetrapib, also nown as CP-529,414 was a drug being developed to treat hypercholesteroleia (elevated cholesterol levels) and prevent cardiovascular disease. Its developent was halted in 2006 when phase III studies showed excessive all-cause ortality in the treatent group receiving a cobination of atorvastatin (Lipitor) and torcetrapib. Torcetrapib acts (as a CETP inhibitor) by inhibiting cholesterylester transfer protein (CETP), which norally transfers cholesterol fro HDL cholesterol to very low density or low density lipoproteins (VLDL or LDL). Inhibition of this process results in higher HDL levels and reduces LDL levels.

保存条件：

-20℃

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安全说明：

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