中文名称: 重组人转铁蛋白(TF)
英文名称: Human Transferrin protein
CAS No:
分子量: 76.6kDa
PZ0313 重组人转铁蛋白(TF) ≥95%(SDS-PAGE) (普西唐-psaitong)
外观与性状:
冻干粉,冻干缓冲液为无菌的 PBS,pH 7.4。
产品简介:
Transferrin (Tf),is an iron transporter, which is mainly biosynthesized in the liver, and it can also be biosynthesized in the brain; i.e., by oligodendrocytes and the choroid plexus, cerebrospinal fluid (CSF) producing tissue. The CSF contains two Tf isoforms, brain-type Tf and serum-type Tf, which differ in their glycan structures. Brain-type Tf is uniquely glycolsylated with biantennary asialo- and agalacto-complex type N-glycans that carry bisecting β1,4-GlcNAc and core α1,6-Fuc.The glycans of serum-type Tf in the CSF are similar to those of Tf in serum. Biochemical analyses reveal that the apparent molecular size of brain-type Tf is smaller than that of serum-type Tf, and that hydrophobic patches are exposed on brain-type Tf as demonstrated by hydrophobic probe binding studies. Research indicates that brain-type Tf levels is decreased in idiopathic normal pressure hydrocephalus, in which CSF production is suspected to decrease, while brain-type Tf increased in spontaneous intracranial hypotension, in which CSF production is suspected to increase. These results suggest that brain-type Tf could be a biomarker of altered CSF production.
检测进行中
产品特点:
采用 LAL 法检测,每 1 μg 蛋白质中的 EU 含量小于 1.0。
保存条件:
本产品为冻干粉形式,建议:将冻干粉的重组人转铁蛋白(TF)产品保存于-20℃以下的干燥环境中。本产品溶解之后,可在4℃保存2-7天,长期使用请置于-20℃以下。为长期保存,推荐添加载体蛋白(0.1% HSA或者BSA),并酌情分装保存,避免反复冻融。
蛋白质ID:
P02787
基因ID:
7018
表达宿主:
人类胚胎肾细胞
蛋白长度:
重组人转铁蛋白由690个氨基酸组成,预测分子量为76.6 kDa。 在还原条件下,SDS-PAGE中人转铁蛋白的表观分子量约为70-100 kDa。
蛋白序列链接:
https://www.uniprot.org/uniprot/P02787
氨基酸序列:
Amino acid sequence derived from Human Transferrin protein isoform (P02787, Met 1-Pro 698) with a polyhistidine tag at the C-terminus was expressed.
种属:
UN码:
HazardClass:
危害声明:
安全说明:
搜索质检报告(COA)
参考文献 & 客户发表文献

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摩尔浓度计算公式

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    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
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    C8=C7/X C8: LOG(C8):