| 中文名称: | PMA | ||||
|---|---|---|---|---|---|
| 英文名称: | PMA | ||||
| 别名: | 佛波醇12-十四酸酯13-乙酸酯 12-O-Tetradecanoylphorbol 13-acetate 4β,9α,12β,13α,20-Pentahydroxytiglia-1,6-dien-3-one 12-tetradecanoate 13-acetate | ||||
| CAS No: | 16561-29-8 | 分子式: | C36H56O8 | 分子量: | 616.83 |
| CAS No: | 16561-29-8 | ||||
| 分子式: | C36H56O8 | ||||
| 分子量: | 616.83 | ||||
一种可逆的高效的蛋白激酶C（PKC）激活剂。PMA (Phorbol-12-Myristate-13-Acetate) is a diester of phorbol and is a tumor promoting compound extracted from croton oil. It is a reversible, highly potent protein kinase C (PKC) activator in vitro and in vivo at nM concentrations. PMA's effects on PKC are attributed to its similarity to diacylgylerol, a natural activator of PKC. PMA activates Ca2+-ATPase and potentiates forskolin-induced cAMP formation. It has been shown to inhibit apoptosis induced by the Fas antigen, but PMA induces apoptosis in HL-60 promyelocytic leukemia cells.
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液，使用的计算公式为：
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为：C1V1 = C2V2 ( 输入 输出 )
