中文名称: | 4--O-甲基和厚朴酚 | ||||
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英文名称: | 4-O-Methyl honokiol | ||||
别名: | 3,5'-diallyl-2'-hydroxy-4-methoxybiphenyl | ||||
CAS No: | 68592-15-4 | 分子式: | C19H20O2 | 分子量: | 280.36 |
CAS No: | 68592-15-4 | ||||
分子式: | C19H20O2 | ||||
分子量: | 280.36 | ||||
MDL: | MFCD19705288 |
包装规格:
10mg in glass bottle
溶解性:
溶于DMSO(100mg/mL超声)
产品描述:
一种从厚朴中分离到的木脂素类化合物,是PPARγ 的激动剂,可抑制 NF-κB 的活性,用于癌症,炎症等研究。 4'-O-Methylhonokiol is a phenol that has been found in M. grandiflora and has diverse biological activities. It is active against the bacteria B. subtilis, S. aureus, and M. smegmatis and the fungus T. mentagrophytes. 4'-O-Methylhonokiol inhibits LPS-induced activation of NF-kB and production of nitric oxide in RAW 264.7 macrophages. In vivo, 4'-O-Methylhonokiol reduces carrageenan-induced paw edema in mice. It reduces neuronal apoptosis and escape latency in the Morris water maze in a mouse model of Alzheimer's disease induced by amyloid-β 1-42 when administered at a dose of 1 mg/kg.3 4-O-methylhonokiol also reduces plasma cholesterol and triglyceride levels, ameliorates hepatic steatosis, and improves insulin resistance in a mouse model of high-fat diet-induced obesity.
保存条件:
-20°C
UN码:
HazardClass:
危害声明:
安全说明:
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参考文献 & 客户发表文献
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )