| 中文名称: | kb NB 142-70 | ||||
|---|---|---|---|---|---|
| 英文名称: | kb NB 142-70 | ||||
| 别名: | kb NB 142-70 kb NB-142-70;9-hydroxy-3,4-dihydrobenzo[4,5]thieno[2,3-f][1,4]thiazepin-5(2H)-one | ||||
| CAS No: | 1233533-04-4 | 分子式: | C11H9NO2S2 | 分子量: | 251.32 |
| CAS No: | 1233533-04-4 | ||||
| 分子式: | C11H9NO2S2 | ||||
| 分子量: | 251.32 | ||||
一种有效的PKD抑制剂，对PKD1、PKD2和PKD3的IC50值分别为28.3nM、58.7nM和53.2nM；亦具有抗癌活性。
kb NB 142-70 is a selective protein kinase D (PKD) inhibitor with IC50 values are 28.3, 58.7 and 53.2 nM for PKD1, 2 and 3 respectively. kb NB 142-70 prevents wound-induced migration of intestinal epithelial cells. PKD1, the most studied member of the PKD family, is implicated in the regulation of a remarkable array of fundamental biological processes, including signal transduction, cell proliferation and differentiation, membrane trafficking, hormone secretion, immune regulation, cardiac hypertrophy, angiogenesis, and cancer.
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液，使用的计算公式为：
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为：C1V1 = C2V2 ( 输入 输出 )
