中文名称: | Dofequidar | ||||
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英文名称: | Dofequidar | ||||
别名: | Dofequidar Dofequidar | ||||
CAS No: | 129716-58-1 | 分子式: | C30H31N3O3 | 分子量: | 481.59 |
CAS No: | 129716-58-1 | ||||
分子式: | C30H31N3O3 | ||||
分子量: | 481.59 |
一种新型的喹啉化合物,能逆转P-糖蛋白(P-gp)介导的多药抗性。
Dofequidar, also known as MS-209, is a quinolone-derived sphingomyelin synthase inhibitor that blocks P-glycoprotein and multidrug resistance-associated protein-1, is under development by Schering for the potential treatment of multidrug resistant tumors. Dofequidar was found to sensitizes cancer stem-like side population cells to chemotherapeutic drugs by inhibiting ABCG2/BCRP-mediated drug export.
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )