中文名称: 蛙皮素
英文名称: Bombesin
CAS No: 31362-50-2
分子式: C71H110N24O18S
分子量: 1619.85
B10851 蛙皮素 ≥98% (psaitong)
包装规格:
25mg in glass bottle
产品简介:
一种最初从青蛙皮肤中分离的十四肽;在胃泌素释放和G蛋白受体活化中起重要作用。
溶解性:
溶于水(1.43mg/mL 超声)
储备液保存:
-80°C, 6 months
-20°C, 1 month
(sealed storage, away from moisture and light)
体外研究:
Bombesin is a tetradecapeptide with a COOH terminus ending in Gly-His-Leu-Met-NH2 and subsequently is shown to closely resemble two mammalian bombesin -related peptides, gastrin-releasing peptide (GRP) and neuromedin B (NMB). Bombesin is found to have stimulatory effects upon gastric and pancreatic secretions, release of gastrointestinal hormones, gallbladder contraction and bronchoconstriction. It is present in amphibian gastric endocrine cells, avian proventriculus endocrine cells and avian brain. In mammals it is present mainly in nerve cells and fibers. The only mammalian endocrine cell shown to date to have bombesin is the P-cell in fetal lung. Bombesin is also found in mammalian brain, with its highest concentration in the hypothalamus. Bombesin is shown to be a potent mitogen for Swiss 3T3 cells. In the presence of a low concentration (3.5%) of serum, bombesin stimulates 3T3 cell proliferation. In serum-free medium, bombesin induces DNA synthesis in the absence of any other added growth factor (IC50=1 nM)].
保存条件:
-20℃
注意事项:
1、为了您的安全和健康,请穿实验服并戴一次性手套操作。
2、以上信息仅做参考交流之用。
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