2020-10-22

1: Hammond SL, Safe S, Tjalkens RB. A novel synthetic activator of Nurr1 induces 
dopaminergic gene expression and protects against 6-hydroxydopamine neurotoxicity 
in vitro. Neurosci Lett. 2015 Oct 21;607:83-9. doi: 10.1016/j.neulet.2015.09.015. 
Epub 2015 Sep 14. PubMed PMID: 26383113; PubMed Central PMCID: PMC4631643.

2: De Miranda BR, Popichak KA, Hammond SL, Jorgensen BA, Phillips AT, Safe S, 
Tjalkens RB. The Nurr1 Activator 1,1-Bis(3'-Indolyl)-1-(p-Chlorophenyl)Methane 
Blocks Inflammatory Gene Expression in BV-2 Microglial Cells by Inhibiting 
Nuclear Factor κB. Mol Pharmacol. 2015 Jun;87(6):1021-34. doi: 
10.1124/mol.114.095398. Epub 2015 Apr 9. PubMed PMID: 25858541; PubMed Central 
PMCID: PMC4429718.

3: De Miranda BR, Popichak KA, Hammond SL, Miller JA, Safe S, Tjalkens RB. Novel 
para-phenyl substituted diindolylmethanes protect against MPTP neurotoxicity and 
suppress glial activation in a mouse model of Parkinson's disease. Toxicol Sci. 
2015 Feb;143(2):360-73. doi: 10.1093/toxsci/kfu236. Epub 2014 Nov 17. PubMed 
PMID: 25406165; PubMed Central PMCID: PMC4306720.

4: De Miranda BR, Miller JA, Hansen RJ, Lunghofer PJ, Safe S, Gustafson DL, 
Colagiovanni D, Tjalkens RB. Neuroprotective efficacy and pharmacokinetic 
behavior of novel anti-inflammatory para-phenyl substituted diindolylmethanes in 
a mouse model of Parkinson's disease. J Pharmacol Exp Ther. 2013 
Apr;345(1):125-38. doi: 10.1124/jpet.112.201558. Epub 2013 Jan 14. PubMed PMID: 
23318470.