| 中文名称: | SB 202190 | ||||
|---|---|---|---|---|---|
| 英文名称: | SB 202190 | ||||
| 别名: | 4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole | ||||
| CAS No: | 152121-30-7 | 分子式: | C20H14FN3O | 分子量: | 331.34 |
| CAS No: | 152121-30-7 | ||||
| 分子式: | C20H14FN3O | ||||
| 分子量: | 331.34 | ||||
| MDL: | MFCD00941964 | ||||
一种高度选择性的有效的和细胞可渗透的p38MAP激酶抑制剂，靶向作用于p38α/β。
SB 202190 is a pyridinyl imidazole that inhibits the p38 pathway. The compound inhibits the isoforms p38α and p38β. SB 202190 has displayed the ability to activate CPP32-like caspases and induce apoptosis. Research demonstrates that when one residue of ERK2, a related p38 not inhibited by pyridinyl imidazoles, is changed it allows SB 202190 to bind. Studies have revealed that SB 202190 can improve leukemia cell growth by activating MEK/MAPK, as well as phosphorylate and activate MLK3.
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液，使用的计算公式为：
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为：C1V1 = C2V2 ( 输入 输出 )
