中文名称: | 3PO 促销 | ||||
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英文名称: | 3PO | ||||
别名: | 3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one 3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one | ||||
CAS No: | 13309-08-5 | 分子式: | C13H10N2O | 分子量: | 210.24 |
CAS No: | 13309-08-5 | ||||
分子式: | C13H10N2O | ||||
分子量: | 210.24 | ||||
MDL: | MFCD00224002 |
一种PFKFB3抑制剂。
3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase) inhibitor. 3PO reduces glycolytic flux and suppresses glucose uptake. 3PO may be useful agents in combination with other drugs that inhibit cancer cell proliferation. PFKFB3 inhibitors suppress glucose uptake, which in turn causes an increase in autophagy. The addition of selective inhibitors of autophagy to 3PO and its more potent derivatives may prove useful as rational combinations for the treatment of cancer.
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )