中文名称: | P7C3-A20 | ||||
---|---|---|---|---|---|
英文名称: | P7C3-A20 | ||||
别名: | 3,6-二溴-BETA-氟-N-(3-甲氧基苯基)-9H-咔唑-9-丙胺;3,6-二溴-beta-氟-N-(3-甲氧基苯基)-9H-咔唑-9-丙胺 P7C3-A20 | ||||
CAS No: | 1235481-90-9 | 分子式: | C22H19Br2FN2O | 分子量: | 506.2 |
CAS No: | 1235481-90-9 | ||||
分子式: | C22H19Br2FN2O | ||||
分子量: | 506.2 | ||||
MDL: | MFCD28023591 |
一种与拉曲匹定(DMEBON)有关的药物,它具有神经保护和促神经原作用。
P7C3 is a drug related to latrepirdine (dimebon), which has neuroprotective and proneurogenic effects, and may be potentially useful for the treatment of Alzheimer's disease and similar neurodegenerative disorders. The precise mechanism of action through which these effects are exerted remains unclear as of 2010, but the pharmacological effects of P7C3 in vitro resemble those of endogenous proneurogenic peptides such as fibroblast growth factor 1, and the proneurogenic activity of P7C3 was around thirty times that of dimebon when they were compared side by side in mice. P7C3 was chosen for further animal studies on the basis of favourable pharmacokinetic factors, such as its high oral bioavailability and long duration of action, but several other related compounds showed similar activity such as the more potent fluorinated analogue P7C3A20 which is up to ten times stronger again, and the methoxy analogue P7C3-OMe, for which it was determined that the (R) enantiomer is the active form.
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )