中文名称: | MLN2238 促销 | ||||
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英文名称: | MLN2238 | ||||
别名: | (R)-(1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutyl)boronic acid | ||||
CAS No: | 1072833-77-2 | 分子式: | C14H19BCl2N2O4 | 分子量: | 361.03 |
CAS No: | 1072833-77-2 | ||||
分子式: | C14H19BCl2N2O4 | ||||
分子量: | 361.03 |
一种潜在的抗肿瘤活性的蛋白酶体抑制剂(PI)。
MLN2238 is a potent proteasome inhibitor (PI) with potential antineoplastic activity. MNL-2238 is also .the biologically active form of MLN9708. MLN2238 has an improved pharmacodynamic profile and antitumor activity compared with bortezomib in both OCI-Ly10 and PHTX22L models. Although both MLN2238 and bortezomib prolonged overall survival, reduced splenomegaly, and attenuated IgG2a levels in the iMyc(Cα)/Bcl-X(L) GEM model, only MLN2238 alleviated osteolytic bone disease in the DP54-Luc model。
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )